Meconic acid
enzyme inhibitor of hepatitis C virus NS5B polymerase
enzyme inhibitor of Catechol-O-Methyl-transferase
https://en.wikipedia.org/wiki/Meconic_acid
enzyme inhibitor of hepatitis C virus NS5B polymerase
enzyme inhibitor of Catechol-O-Methyl-transferase
https://en.wikipedia.org/wiki/Meconic_acid
Fluorescent probe for nonpolar cavities in proteins. Used to detect Aβ fibre (Kd = ~80 nM); exhibits distinct fluorescent profiles for fibres and oligomers. Fluoresces in hydrophobic media, negligible fluorescence in water solutions. Excitationemission λ ~ 355520 nm at pH 7.4.s
Homobifunctional cross-linking reagent; e.g. isolation of insulin receptor
DSG is disuccinimidyl glutarate, a simple homobifunctional crosslinker builded on the amine-reactive N-hydroxysuccinimide (NHS) ester group at both sidws of a 7.7 angstrom spacer arm. It is used for crosslinking the amine moiety of several molecules. DSG is cell membrane-permeable and it is used in ChIP assays to determine DNA-protein binding interactions.
References:
http://europepmc.org/articles/PMC5669458/
https://www.nature.com/articles/srep14086?proof=true