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This molecule is an amine-reactive homobifunctional cross-linker. It rapidly attacks solvent accessible lysine-NH2 groups at neutral or slightly basic pH. DSA can generate additional structural information about protein structure while generally less often used than DSG or DSS.


CoA BC366de3

DAPpNP from Synchem

p-Nitrophenyl 3-diazopyruvate

The heterobifunctional cross-linking agent p-nitrophenyl 3-diazopyruvate (DAPpNP) is used for the synthesis of photoaffinity probes and photoactivatable cross-linking agents that are nucleophile specific.