S-Acetylthioglycolic acid N-hydroxysuccinimide ester
SATA (N-succinimidyl S-acetylthioacetate, CAS# 76931-93-6) is an important crosslinking reagent in biochemistry. It is primarily used to introduce protected thiol groups (sulfhydryl groups) into proteins, peptides, or other amine-containing molecules.
SATA reacts with primary amines on target molecules (e.g., lysine side chains in proteins), linking them to a protected thiol group. Subsequent addition of hydroxylamine removes the protecting group, yielding a free, reactive sulfhydryl group. This group can then be stably coupled to maleimide-activated proteins.
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NHS-APDP
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Heptanedioic acid 1,7-bis(2,5-dioxo-1-pyrrolidinyl) ester
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DSSeb
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Di(N-succinimidyl) malonate
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Suberic acid bis(N-succinimidyl) ester
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Nonanedioic acid 1,9-bis(2,5-dioxo-1-pyrrolidinyl) ester
