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Orlistat

biochemical

A nonabsorbed inhibitor of gastric and pancreatic lipases, that potently inhibits lipoprotein lipase, monoacylglycerol lipase and diacylglycerol lipase.

It decrease systemic absorption of dietary fat

It is a saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini