Showing 1–9 of 201 results

Coelenterazine native

Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia and aequorins. It is commonly used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.

https://en.wikipedia.org/wiki/Coelenterazine

CoA S053

MSDS S053

SANH

Hydrazine-based and carbonyl-based bifunctional crosslinking reagents for biomolecules, drugs, and synthetic polymers

 

CoA BC366de35

MSDS BC366DE35

S-HyNic Crosslinker

The S-HyNic (succinimidyl-6-hydrazino-nicotinamide) heterobifunctional crosslinker is fundamental to Chromaling. S-HyNic reacts with primary amines of proteins (amino group of glycine) or amino-modified oligonucleotides or surfaces, introducing a HyNic (6-hydrazinonicotinamide) linker that forms stable covalent conjugates with biomolecules possessing 4FB (4-formylbenzamide) incorporated linkers.

CoA S-HyNic Crosslinker

MSDS A252

References:

https://www.researchgate.net/scientific-contributions/39596054_M_J_Baas

 

 

D-Luciferin free acid

D-Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. The water soluble substrate for the firefly luciferase enzyme uses ATP and Mg-Ion as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death indicator.

Luciferin is a common reagent used throughout the biotechnology family and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. This is often made by the use of the D-Luciferin sodium salt (BC218), because of it`s good solubility in water and tolerance of living organism. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin.

 

CoA D-Luciferin free acid

MSDS S039

References:

http://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=21&ved=0ahUKEwikr56P7YLcAhVEFiwKHWAEBlY4FBAWCDcwAA&url=http

%3A%2F

%2Fcancerres.aacrjournals.org%2Fhighwire%2Ffilestream%2F290528%2Ffield_highwire_adjunct_files%2F0%2FMatsMetsFigs1-5.pdf&usg=AOvVaw3e

GNSYFHf8vdVE5u80HMkr

http://www.wmis.org/abstracts/2012/data/papers/P293.html

http://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=23&ved=0ahUKEwikr56P7YLcAhVEFiwKHWAEBlY4FBAWCEAwAg&url=http

%3A%2F

%2Fwww.pnas.org%2Fhighwire%2Ffilestream%2F617093%2Ffield_highwire_adjunct_files%2F4%2Fpnas.201411295SI.pdf&usg=AOvVaw0D10lUikyDN

OpNB4wisC4M

http://aem.asm.org/content/74/22/7023.full

fireflies in action

8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt

APTS is a fluorescence reagent that has a high level of detection sensitivity for sugars. The LOD for APTS-derivatized sugars has been proven to be 0.4 nM when using a 488 nm laser. The tri-anionic nature of APTS makes it ideal for the studies of carbohydrate molecules and small hormone molecules by high resolution capillary electrophoresis.

CoA BC032

MSDS BC032