Der Beitrag 6-Amino-6-deoxyluciferin erschien zuerst auf Synchem.

Luciferin is a common reagent used throughout the biotechnology family and specifically for in vivo imaging. Luciferase labeled tumor cells, stem cells or infectious diseases are often inoculated into research animals such as rats or mice for investigation. This is often made by the use of the D-Luciferin sodium salt (BC218), because of it`s good solubility in water and tolerance of living organism. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI).

Luciferin is also commonly used for in vitro research, including luciferase and ATP assays, gene reporter assays, high throughput sequencing and various contamination assays.

Firefly Luciferin is identical to Beetle Luciferin.

CoA D-Luciferin free acid

MSDS S039

References:

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.03097/full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566035/

http://aem.asm.org/content/74/22/7023.full

fireflies in action

Der Beitrag D-Luciferin free acid erschien zuerst auf Synchem.

The mechanism and applications of D-Luciferin potassium salt (order# BC219) are typical in an ATP-dependent reaction, where luciferase catalyzes the oxidation of D-luciferin to oxyluciferin, yielding a high-intensity bioluminescent signal.

This reaction of the D-Luciferin potassium salt (order# BC219) is fundamental for:

• In Vivo Bioluminescence Imaging (BLI): Monitoring tumor growth, gene expression, and therapeutic efficacy in living animal models due to the substrate's excellent bioavailability and tissue penetration.
• Reporter Gene Assays: Quantifying gene expression levels in transfected cell lines with high signal-to-noise ratios.
• ATP & Cell Viability Analysis: Detecting metabolic activity and infinitesimal levels of ATP in various biological samples.
• Pathogen Tracking: Real-time visualization of bacterial or viral infections in preclinical research.

Our D-Luciferin potassium salt BC219 (the potassium salt of the free acid S039) is wordwide used in the cancer research. A lot of researchers have used our high quality D-Luciferin potassium salt so far.

You can find more information by searching for the key words "materials and methods" together with "D-Luciferin" and "Synchem".

The CoA BC219 is typical; high quality is guaranteed.

MSDS BC219

You can order and pay with creditcard using our shop or you may simple send us an email: info@synchem.de

The D-Luciferin free acid S039 and the sodium salt BC218 are also in stock and can be sent immediately.

Freight charge depends on the country and will be given during the order process.

Der Beitrag D-Luciferin potassium salt erschien zuerst auf Synchem.

MSDS BC218

CoA BC218

Der Beitrag D-Luciferin sodium salt erschien zuerst auf Synchem.

A blue emitting Rluc substrate for BRET studies

Der Beitrag BlueSyn C erschien zuerst auf Synchem.

https://en.wikipedia.org/wiki/Coelenterazine

CoA S053

MSDS S053

Der Beitrag Coelenterazine native erschien zuerst auf Synchem.